Introducing TRU NIAGEN® by ChromaDex.

A unique form of vitamin B3 clinically proven to safely increase your cell’s ability to make energy, with NAD.

What is NAD?

NAD, or nicotinamide adenine dinucleotide, is a molecule found in every cell in the human body. Its core purpose is to help the mitochondria – the ‘powerhouse' of the cell, convert food into the energy. Additionally, NAD is required to “turn off” genes implicated in accelerating aging processes.

That's where TRU NIAGEN® comes in. The key ingredient in TRU NIAGEN® is NIAGEN® nicotinamide riboside (NR)— a cutting-edge form of vitamin B3 proven to significantly increase NAD levels.

The metabolism of nicotinamide riboside is unique from that of more common forms of vitamin B3, nicotinamide and nicotinic acid (niacin).

"NAD+ is one of the critical components of the Krebs cycle, the biochemical pathway that creates ATP; the body’s energy source.

Increasing NAD levels can translate into increased energy, mental clarity and focus, memory, and a general feeling of youthfulness."

– Terry Grossman, M.D.

TRU NIAGEN® & Healthy Aging.

NR supplementation increases NAD+, which activates several enzymes critical for health, like:

  • CD38, a receptor involved in glucose-induced insulin secretion
  • Sirtuins, an anti-aging enzymes
  • PARPs, which repair damaged DNA

NR accomplishes this by stimulating mitochondrial biogenesis and improving mitochondrial health. Therefore, NR supplementation supports tissues that are heavily reliant on the mitochondria for energy, like our liver, nervous system, heart and muscles.

Benefits of NAD

NAD is essential to supporting many aspects of healthy aging:

  • Increases cellular metabolism and energy production
  • Maintains healthy cholesterol levels already within the normal range
  • NAD supports muscle function, including maintenance of muscle mass
  • Helps maintain health, longer

Mechanism of Action

The primary role of NR, as well as NA and NAM, is to serve
as precursors of the essential coenzyme nicotinamide adenine dinucleotide (NAD).

  • NR is transported directly into cells via nucleoside transporters6, where it is converted to NAD through a distinct, two-step biosynthetic pathway.
  • NR raises intracellular NAD levels with superior pharmacokinetics compared to NA and NAM.7

Over 150 scientific articles have been published on TRU NIAGEN®'s ingredient since its discovery in 2004.

Research Behind NAD

NAD & Aging

By age 60, your body's ability to produce NAD roughly halves of what it produces in your 40s.

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NAD & Sleep

Our body's production of NAD follows the natural cycle of our circadian rhythm, helping everything stay in syn.

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NAD & Fat

NAD assists in fat burning by turning into the hydrogen-carrying versoin of itself (NADH) to process turn food and drinks into energy.

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NAD & Alcohol

NAD plays an important role in a two-step process that 1) Detoxifies alcohol into sugar, and 2) Helps turn that sugar into energy.

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NAD & Muscle

NAD is required for muscle recovery after strenuous exercise.

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NAD & Breathing

NADPH plays a critial role in denfending against oxidative stress.

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