{"title":"Mental Health Supplements for Fall","description":"No code needed at checkout to save 15% off Transcend Mental Health Supplements Collection. Not valid on Subscribe and Save.\u003ci data-mce-fragment=\"1\"\u003e*Promotional Disclaimer:\u003c\/i\u003e Only applies to One-Time Purchases of this collection's products made between 10:00 am EDT, October 20th 2022 through 11:30 pm EDT October 31st, 2022. Cannot be applied to past purchases, no exceptions. Promotion only valid for a limited time, and may not be combined with any other sale, promotion, discount, code, coupon and\/or offer. Not valid for Subscribe and Save.","products":[{"product_id":"melatonin-sleep-supplement","title":"Melatonin","description":"\u003ch5\u003eDescription\u003c\/h5\u003e\n\u003cul class=\"callout-box\"\u003e\n\u003cli\u003eFound to extend the life span of laboratory animals 25 percent\u003csup\u003e4,5,6\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003eDisplays powerful anti-oxidant properties\u003csup\u003e7\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003eShown to stimulate the immune system\u003csup\u003e8\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003eExcellent treatment for jet lag\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eMelatonin is widely regarded as the \"hormone of sleep.\" It is a light-sensitive hormone secreted rhythmically by the pineal gland located deep within the brain. The level of melatonin in the bloodstream is low through the daylight hours and begins to rise in the early evening, priming the brain for sleep.\u003csup\u003e1\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003eSleep is critical to good health, yet more than one-third of Americans report some type of sleep disturbance and over 20 million have occasional insomnia. Sleep deprivation for a prolonged period of time can lead to stress and depression of immune function.\u003c\/p\u003e\n\u003cp\u003eMelatonin is useful for maintaining healthy sleep patterns.\u003csup\u003e2,3\u003c\/sup\u003e However, the effects of melatonin on the body are far greater than merely promotion of sleep.\u003c\/p\u003e\n\u003cp\u003eMelatonin secretion peaks at age seven, then declines precipitously during adolescence. At about age 45, the pineal gland begins to shrink and loses the cells that produce melatonin. Hormone production becomes erratic such that by age 60, melatonin production is down to half of youthful levels. This contributes to the sleep difficulties experienced by so many seniors. In addition, the drop in melatonin alerts the other glands and organ systems that the time has come to wind down. In women, the ovaries stop functioning, levels of estrogen drops, and women enter menopause. In men, the testes slow down production of hormones, and although sperm are still produced, the production of testosterone declines. In both sexes, immune system function declines. \u003c!--increasing vulnerability to diseases ranging from infections to cancer to autoimmune ailments, where the body’s immune system turns on and attacks its own tissues.\/--\u003eThe other organs and body systems follow suit, and we begin the downward slide associated with aging.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e*Not allowed for import in Japan, Austria, Iceland, France and Czech Republic.\u003c\/p\u003e\n\u003ch5\u003eIngredients\u003c\/h5\u003e\n\u003cmeta charset=\"utf-8\"\u003e\n\u003ch6\u003eOther Ingredients:\u003c\/h6\u003e\n\u003cspan\u003e Dextrose, microcrystalline, cellulose, silicon dioxide and vegetable stearate.\u003c\/span\u003e\n\u003ch6\u003eWARNING:\u003c\/h6\u003e\n\u003cspan\u003eThis product is manufactured and packaged in a facility which may also process milk, soy, wheat, egg, peanuts, tree nuts, fish and crustacean shellfish.\u003c\/span\u003e\n\u003ch6\u003eCAUTION:\u003c\/h6\u003e\n\u003cspan\u003eDo not exceed recommended dose. This product is not intended for pregnant or nursing mothers, children under 18, or individuals taking any prescription medication including anti-depressants. Reduce dose if drowsiness occurs. Avoid driving or performing other potentially dangerous tasks while taking this formula. If you have questions about the advisability of taking this product, consult a physician prior to use.\u003c\/span\u003e\n\u003ch6\u003eDosage:\u003c\/h6\u003e\n\u003cspan\u003eOne 3 mg tablet 30-60 minutes before bed\u003c\/span\u003e\n\u003cp\u003eContains No Animal Products, Yeast, Sugar, Starch, Artificial Colors, Flavors or Preservatives.\u003c\/p\u003e\n\u003cp\u003eRay \u0026amp; Terry’s Chewable Melatonin contains 120 tablets per bottle.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch5\u003eReferences\u003c\/h5\u003e\n\u003cmeta charset=\"utf-8\"\u003e\n\u003col class=\"supfact\"\u003e\n\u003cli\u003e\n\u003cspan\u003e\u003ca\u003eNeuroimage.\u003c\/a\u003e\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e2006 May 15;31(1):410-8. Epub 2006 Jan 20. Gorfine T et al.\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eAm J Med\u003c\/span\u003e. 2004 Jan 15;116: 91–95. D. Leger et al.\u003c\/li\u003e\n\u003cli\u003e\n\u003ca\u003e\u003cspan\u003eVertex\u003c\/span\u003e.\u003c\/a\u003e\u003cspan\u003e \u003c\/span\u003e2007 Jul-Aug;18(74):288-93. Cardinali DP.\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eJ Pineal Res\u003c\/span\u003e. 2007 Mar;42(2):153-8.\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"http:\/\/www.ncbi.nlm.nih.gov\/sites\/entrez?Db=pubmed\u0026amp;Cmd=Search\u0026amp;Term=%22Kedziora-Kornatowska%20K%22%5BAuthor%5D\u0026amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstractPlusDrugs1\"\u003eKedziora-Kornatowska K\u003c\/a\u003e\u003cspan\u003e \u003c\/span\u003eet al.\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eExp Gerontol\u003c\/span\u003e. 2001 Jul;36(7): 1083–1100. Y. Touitou.\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eExp Gerontol\u003c\/span\u003e. 2002 May;37(5):629-38. Bonilla E et al.\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eBiol Signals\u003c\/span\u003e. 1998 Jan;7(1): 61–72.F. Fraschini et al.\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eReprod Nutr Dev\u003c\/span\u003e. 1999 May-Jun;39(3):383-98. Nelson RJ, Drazen DL.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e \u003c\/p\u003e","brand":"Vitalabs","offers":[{"title":"Default Title","offer_id":7563498127421,"sku":"RNT280-8-1","price":13.97,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0012\/6065\/0557\/products\/Melatonin_mockup.jpg?v=1536789233"},{"product_id":"vitamin-b-12-sublingual","title":"Vitamin B-12, Sublingual","description":"\u003cdiv style=\"text-align: center;\"\u003e\u003cspan style=\"color: #2b00ff;\"\u003e\u003c\/span\u003e\u003c\/div\u003e\n\u003ch5\u003e\u003c\/h5\u003e\n\u003ch5\u003eDescription\u003c\/h5\u003e\n\u003cul class=\"callout-box\"\u003e\n\u003cli\u003eIncreased energy\u003c\/li\u003e\n\u003cli\u003eImprove mood\u003c\/li\u003e\n\u003cli\u003eFight fatigue\u003c\/li\u003e\n\u003cli\u003eCommon deficiency\u003c\/li\u003e\n\u003cli\u003eBetter absorption\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eVitamin B12\u003c\/strong\u003e (also called cobalamin) is one of eight water-soluble B vitamins. It plays an important role in DNA and RNA synthesis and is needed to synthesize S-adenosylmethionine (SAMe), which helps the immune system function properly and affects mood.\u003csup\u003e1\u003c\/sup\u003e B12 is necessary for normal nerve cell activity and the creation of red blood cells.\u003csup\u003e2\u003c\/sup\u003e B vitamins are used when converting carbohydrates into glucose to produce energy.\u003csup\u003e3\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003eB12 is often called an \"anti-stress\" vitamin because it is believed to enhance the activity of the immune system and improve the body's ability to withstand stressful conditions.\u003csup\u003e4\u003c\/sup\u003e Vitamin B12 deficiency is linked to fatigue, irritability, and impaired memory.\u003csup\u003e5\u003c\/sup\u003e Supplementation with Vitamin B12 may assist in increasing energy levels, improving mood, and fighting fatigue.\u003csup\u003e6\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003eThe ability to absorb B12 decreases with age. In one study, 15 percent of adults over 65 years of age showed evidence of B12 deficiency. This may be attributed to the common use of gastric acid-blocking agents, which may inhibit the release of B12 during digestion. B12 deficiency is also common in strict vegetarians and people that have had stomach surgery.\u003csup\u003e7\u003c\/sup\u003e\u003c\/p\u003e\n\u003ch5\u003eIngredients\u003c\/h5\u003e\n\u003ch6\u003eOther Ingredients:\u003c\/h6\u003e\n\u003cp\u003eSorbitol, fructose, mannitol, croscarmellose sodium, natural cherry flavor, silicon dioxide, lecithin, and vegetable magnesium stearate.\u003c\/p\u003e\n\u003ch6\u003eALLERGEN WARNING:\u003c\/h6\u003e\n\u003cspan\u003e CONTAINS SOY (LECITHIN)\u003c\/span\u003e\n\u003ch6\u003eCAUTION:\u003c\/h6\u003e\n\u003cspan\u003eDo not exceed recommended dose. Pregnant or nursing mothers, children under 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.\u003c\/span\u003e\n\u003ch6\u003eSuggested Use:\u003c\/h6\u003e\n\u003cp\u003e1 tablet taken 1 to 3 times daily preferably with meals or as directed by a healthcare professional. For best results, chew tablet thoroughly before swallowing. TRANSCEND's Vitamin B-12 contains 100 tablets per bottle.\u003c\/p\u003e\n\u003cmeta charset=\"utf-8\"\u003e\n\u003ch5 class=\"supfact\"\u003e\u003cspan\u003eMore Info\u003c\/span\u003e\u003c\/h5\u003e\n\u003cmeta charset=\"utf-8\"\u003e\n\u003cp\u003eFolic acid (folate) is also essential to DNA synthesis. It is one of the few nutrients that works better when taken as a separate supplement than as part of food. Folic acid is included in TRANSCEND's B12 supplement because of their intertwined functions.\u003c\/p\u003e\n\u003cp\u003eIt is very difficult to properly absorb B12 through the digestive tract. For this reason, the vitamin is often taken intravenously, which can be inconvenient, painful and expensive. Our sublingual product is designed to absorb quickly into the system by dissolving under the tongue and entering the bloodstream directly. This method allows for maximum absorption of the B12.\u003c\/p\u003e\n\u003cp\u003eFrom the FDA's website: \"As part of a well-balanced diet that is low in saturated fat and cholesterol, Vitamin B12 may reduce the risk of vascular disease. FDA evaluated the above claim and found that, while it is known that diets low in saturated fat and cholesterol reduce the risk of heart disease and other vascular diseases, the evidence in support of the above claim is inconclusive.\"\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch5 class=\"supfact\"\u003e\u003cspan\u003eReferences\u003c\/span\u003e\u003c\/h5\u003e\n\u003col class=\"supfact\"\u003e\n\u003cli\u003e\n\u003cspan\u003eVirtual Mentor.\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003eJune 2006, Volume 8, Number 6: 392-396. Reenan, J.\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eAm Fam Physician\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e2003;67:979-86,993-4. Oh, Robert, et al.\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eJ. Biol. Chem.\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003eLing and Chow 206 (2): 797. August 1953\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eAnn\u003c\/span\u003e\u003cspan\u003eNY Acad Sci 1990;585: pp.513-5\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003eWhitney, Eleanor Noss, and Rolfes, Sharon Rady (2002).\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eUnderstanding Nutrition,\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e9th edition. Belmont, CA: Wadsworth\/Thomson Learning\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eNeuropsychopharmacology\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e(1996) 15 456-464. Mayer, G. et al.\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eN Engl J Med December 20, 2001;345: pp. 1819-1824\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e \u003c\/p\u003e","brand":"TranscendMe","offers":[{"title":"Default Title","offer_id":7563499503677,"sku":"RNT315-7-1","price":17.59,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0012\/6065\/0557\/products\/Transcend-Vitamin-B12.jpg?v=1544730144"},{"product_id":"mood-support","title":"Mood Support","description":"\u003ch5 style=\"color: #ff0000;\"\u003e\u003cspan style=\"color: #000000;\"\u003eDescription\u003c\/span\u003e\u003c\/h5\u003e\n\u003ch2\u003e\u003cspan\u003eA Kurzweil + Grossman Formula\u003c\/span\u003e\u003c\/h2\u003e\n\u003cul class=\"callout-box\"\u003e\n\u003cli\u003eStimulate serotonin production\u003c\/li\u003e\n\u003cli\u003eImprove outlook and mood\u003c\/li\u003e\n\u003cli\u003eSupport healthy sleep patterns\u003c\/li\u003e\n\u003cli\u003eNatural formula for a balanced life\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eIn modern society, many people experience a low level of stress almost continuously. Long term stress can induce a constant flow of the stress hormone cortisol when it really isn't needed and the results can be toxic. Your body has to work hard to counter the effects of elevated cortisol levels, resulting in digestive disorders, leaving you more susceptible to disease.\u003c\/p\u003e\n\u003cp\u003eStress can contribute to a lack of quality sleep, which can cause weight gain, decrease your energy, raise your blood pressure, and increase the risk of heart disease. It can suppress your immune system which can increase the risk of cancer and other diseases. And, working in a vicious circle, inadequate sleep can wreck your mood and ability to concentrate.\u003c\/p\u003e\n\u003cp\u003eMaintaining a healthy mood by minimizing anxiety and getting an adequate amount of quality sleep is important to maintaining a balanced life.\u003c\/p\u003e\n\u003cp\u003eMood Support was reformulated from previous formulas. It no longer contains SAM-e due to indications that the ingredient is not effective in small amounts. The new formulation is deemed more efficient without this ingredient.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch5\u003eIngredients\u003c\/h5\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch6\u003eOther Ingredients: \u003c\/h6\u003e\n\u003cp\u003e\u003cspan\u003eMicrocrystalline cellulose, vegetable cellulose (with chlorophyll), vegetable stearic acid, vegetable magnesium stearate, silicon dioxide and natural vanilla flavor (added for aroma).\u003c\/span\u003e\u003c\/p\u003e\n\u003ch6\u003eCAUTION: \u003c\/h6\u003e\n\u003cp\u003e\u003cspan\u003eDo not exceed recommended dose. Avoid driving or operating heavy machinery while taking this product. Not recommended for pregnant or nursing mothers or children under 18 years of age. Not for use by individuals with a known medical condition including liver disease, bipolar (manic)depression or anyone taking prescription medications including anti-depressants, anti-coagulants or MAO inhibitors. If you have questions about the advisability of taking this product, consult your physician prior to use.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch6\u003eWARNING:\u003c\/h6\u003e\n\u003cp\u003e\u003cspan\u003e This product is manufactured and packaged in a facility which may also process milk, soy, wheat, egg, peanuts, fish and crustacean shellfish.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch6\u003eDosage:\u003c\/h6\u003e\n\u003cp\u003e\u003cspan\u003e Take one vegetarian capsule 1 to 2 times daily with meals as a dietary supplement, or as directed by your physician.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eRay \u0026amp; Terry's Mood\/Sleep Support\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003econtains 60 vegetarian capsules per bottle\u003c\/span\u003e.\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"mso-margin-top-alt: auto; mso-margin-bottom-alt: auto;\"\u003e\u003cstrong\u003e\u003cspan style=\"font-size: 11.0pt; mso-ascii-font-family: Calibri; mso-ascii-theme-font: minor-latin; mso-hansi-font-family: Calibri; mso-hansi-theme-font: minor-latin; mso-bidi-font-family: Calibri; mso-bidi-theme-font: minor-latin; color: #333333; background: white; mso-bidi-font-style: italic;\"\u003e*California residents – ingredients in this product may exceed Prop 65 limits and shipments’ contents may carry notice of this caution. Please contact \u003ca href=\"mailto:info@transcend.me\"\u003e\u003cspan style=\"color: #344651;\"\u003esupport@transcend.me\u003c\/span\u003e\u003c\/a\u003e for further information.\u003c\/span\u003e\u003c\/strong\u003e\u003cspan style=\"font-size: 11.0pt; mso-ascii-font-family: Calibri; mso-ascii-theme-font: minor-latin; mso-fareast-font-family: 'Times New Roman'; mso-hansi-font-family: Calibri; mso-hansi-theme-font: minor-latin; mso-bidi-font-family: Calibri; mso-bidi-theme-font: minor-latin;\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch5\u003eMore Info \u003c\/h5\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003eNatural supplements can be helpful to promote healthy sleep patterns and maintain a positive outlook without the side effects that can accompany pharmaceutical methods.\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eRay \u0026amp; Terry's Mood \u0026amp; Sleep Support\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003econtains B vitamins, GABA, DMAE, 5-HTP, chamomile, and ashwagandha extract.\u003c\/p\u003e\n\u003cp\u003eDeficiencies in various\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eB vitamins\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003ecan contribute to: tiredness, nervousness, irritability, occasional insomnia, and dizziness.\u003csup\u003e1\u003c\/sup\u003e\u003cspan\u003e \u003c\/span\u003eIn particular, B12 has been called an \"anti-stress\" vitamin because it is believed to enhance the activity of the immune system and improve the body's ability to withstand stressful conditions.\u003csup\u003e2\u003c\/sup\u003e\u003cspan\u003e \u003c\/span\u003eVitamin B12 deficiency has been linked to fatigue, irritability, and impaired memory.\u003csup\u003e3\u003c\/sup\u003eSupplementation with Vitamin B12 may assist in increasing energy levels, improving mood, and fighting fatigue.\u003csup\u003e4\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eGABA\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e(gamma-aminobutyric acid) is a key neurotransmitter that can act as a mild tranquilizer. This natural substance is non habit forming and is effective at relieving stress and maintaining a calm mood.\u003csup\u003e5\u003c\/sup\u003e\u003cspan\u003e \u003c\/span\u003eGABA can cause drowsiness and can help promote better quality sleep.\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eDMAE \u003c\/span\u003e(dimethylaminoethanol) is an organic compound related to choline and is a precursor to the neurotransmitter acetylcholine. Supplements containing DMAE have been observed both psychologically and physiologically to help improve outlook and mood.\u003csup\u003e6\u003c\/sup\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e5-HTP\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e(5-hydroxytryptophan) is an amino acid produced in the body and involved in nervous system health.\u003csup\u003e7\u003c\/sup\u003e\u003cspan\u003e \u003c\/span\u003eVitamin B6 works with 5-HTP to synthesize serotonin, an important neurotransmitter also affecting mood and sleep patterns.\u003csup\u003e8\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003eHerbs such as\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eChamomile \u003c\/span\u003eand\u003cspan\u003e Ashwagandha \u003c\/span\u003ehelp promote healthy sleep patterns and aid in relaxation. Chamomile has been shown to create a mild sedative effect and is often used to ease anxiety.\u003csup\u003e9\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThe Improved Formula:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eNow in a vegetarian capsule\u003c\/li\u003e\n\u003cli\u003eSt. John's Wort has again returned to the formula, due to the most current research\u003c\/li\u003e\n\u003cli\u003e5-HTP is very effective, so we increased the amount per capsule\u003c\/li\u003e\n\u003cli\u003eDue to recent research, we reduced the folic acid content to avoid excess when combining with other formulas\u003c\/li\u003e\n\u003cli\u003eNiacinamide was reduced to minimize flushing and other concerns\u003cspan\u003e \u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003eValerian root was replaced with Ashwagandha extract, an effective and odorless herb\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch5\u003eReferences\u003c\/h5\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003eWardlaw, Gordon M.; Hampl, Jeffrey S.; and Disilvestro, Robert A. (2004).\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003ePerspectives in Nutrition,\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e6th edition. New York: McGraw-Hill.\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eAnnNY Acad Sci 1990;585: pp.513-5\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003eWhitney, Eleanor Noss, and Rolfes, Sharon Rady (2002).\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eUnderstanding Nutrition,\u003c\/span\u003e9th edition. Belmont, CA: Wadsworth\/Thomson Learning\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eNeuropsychopharmacology\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e(1996) 15 456-464. Mayer, G. et al.\u003c\/li\u003e\n\u003cli\u003eCurr Opin Pharmacol. (February 2006). 6(1): 7-17. \"Glutamate- and GABA-based CNS therapeutics.\" Foster AC, Kemp JA.\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eEur J Med Res\u003c\/span\u003e. 2003 May 30;8(5):183-91. \"Efficacy of dimethylaminoethanol (DMAE) containing vitamin-mineral drug combination on EEG patterns in the presence of different emotional states.\" Dimpfel W, Wedekind W, Keplinger I.\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eCochrane Database Syst Rev\u003c\/span\u003e. 2002;(1):CD003198. \"Tryptophan and 5-hydroxytryptophan for depression.\" Shaw K, Turner J, Del Mar C.\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eScience\u003c\/span\u003e. 2003 Jul 18;301(5631):386-9. \"Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene.\" Caspi A, Sugden K, Moffitt TE, Taylor A, Craig IW, Harrington H, McClay J, Mill J, Martin J, Braithwaite A, Poulton R.\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eBiol Pharm Bull\u003c\/span\u003e. 2005 May;28(5):808-10. \"Hypnotic activities of chamomile and passiflora extracts in sleep-disturbed rats.\" Shinomiya K, Inoue T, Utsu Y, Tokunaga S, Masuoka T, Ohmori A, Kamei C.\u003c\/li\u003e\n\u003c\/ol\u003e","brand":"Vitalabs","offers":[{"title":"Default Title","offer_id":7563509497917,"sku":"RNT065-1-1","price":21.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0012\/6065\/0557\/products\/Transcend-Mood-Sleep-Support.jpg?v=1546899173"},{"product_id":"gaba-brain-sleep-supplement","title":"GABA","description":"\u003ch5\u003eDescription\u003c\/h5\u003e\n\u003cul class=\"callout-box\"\u003e\n\u003cli\u003eImprove mood\u003c\/li\u003e\n\u003cli\u003eAlleviate anxiety\u003c\/li\u003e\n\u003cli\u003eMaintain healthy sleeping patterns\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: bold;\"\u003eGABA\u003c\/span\u003e ( γ-Aminobutyric acid) is the primary inhibitory neurotransmitter in the nervous system of humans and other mammals. It is needed to regulate neuron activity and is involved in many tissues and organs outside the brain as well as the regulation of muscle tone.\u003csup\u003e1\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003eDuring fetal development, GABA acts as a nerve growth factor and has an important role in sending signals that keep brain cells alive.\u003csup\u003e2\u003c\/sup\u003e It also regulates the growth and production of neural progenitor cells, which are similar to adult stem cells in that they can differentiate to become a specific type of cell.\u003csup\u003e3\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003eSynapses are connections between neurons that allow information to pass back and forth. GABA is integrally involved in the formation of synapses and is needed for neurons to properly exchange information.\u003csup\u003e4\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003csup\u003e \u003c\/sup\u003e\u003c\/p\u003e\n\u003cmeta charset=\"utf-8\"\u003e\n\u003ch5\u003eIngredients \u003c\/h5\u003e\n\u003cmeta charset=\"utf-8\"\u003e\n\u003ch6\u003eOther Ingredients: \u003c\/h6\u003e\n\u003cspan\u003eCellulose (capsule), Rice Flour, Silica and Magnesium Stearate (vegetable source).\u003c\/span\u003e\n\u003cp\u003eGABA (gamma aminobutyric acid) is a non-essential amino acid found mainly in the human brain and eyes. It is considered an inhibitory neurotransmitter, which means it regulates brain and nerve cell activity by inhibiting the number of neurons firing in the brain. GABA is referred to as the \"brain's natural calming agent\". By inhibiting over-stimulation of the brain, GABA may help promote relaxation and ease nervous tension.\u003c\/p\u003e\n\u003ch6\u003eSuggested Use:\u003c\/h6\u003e\n\u003cspan\u003eTake 1 capsule 2 to 3 times daily as needed, preferably with juice or water on an empty stomach.\u003c\/span\u003e\n\u003ch6\u003eCAUTION:\u003c\/h6\u003e\n \u003cspan\u003eDo not exceed recommended dose. This product is not intended for pregnant or nursing mothers, children under the age of 18, or persons with a known medical condition. If you have questions about the advisability of taking this product, consult your physician prior to use. This product is manufactured and packaged in a facility which may also process milk, soy, wheat, egg, peanuts, tree nuts, fish and crustacean shellfish.\u003c\/span\u003e\n\u003ch6\u003eContains No:\u003c\/h6\u003e\n\u003cspan\u003eAnimal Products, Yeast, Sugar, Starch, Artificial Colors, Flavors or Preservatives.\u003c\/span\u003e\n\u003cp\u003eTRANSCEND's GABA 500 mg contains 100 veggie capsules per bottle.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cmeta charset=\"utf-8\"\u003e\n\u003ch5\u003eReferences\u003c\/h5\u003e\n\u003cmeta charset=\"utf-8\"\u003e\n\u003col type=\"1\" start=\"1\"\u003e\n\u003cli\u003eWatanabe M, Maemura K, Kanbara K, Tamayama T, Hayasaki H.\"GABA and GABA receptors in the central nervous system and other organs.\"\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eInt Rev Cytol\u003c\/span\u003e. 2002;213:1-47.\u003c\/li\u003e\n\u003cli\u003eGanguly K, Schinder AF, Wong ST, Poo M. \"GABA itself promotes the developmental switch of neuronal GABAergic responses from excitation to inhibition.\"\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eCell\u003c\/span\u003e. 2001 May 18;105(4):521-32.\u003c\/li\u003e\n\u003cli\u003eHaydar TF, Wang F, Schwartz ML, Rakic P. \"Differential modulation of proliferation in the neocortical ventricular and subventricular zones.\"\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eJ Neurosci\u003c\/span\u003e. 2000 Aug 1;20(15):5764-74.\u003c\/li\u003e\n\u003cli\u003eBen-Ari Y. \"Excitatory actions of gaba during development: the nature of the nurture.\"\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eNat Rev Neurosci\u003c\/span\u003e. 2002 Sep;3(9):728-39.\u003c\/li\u003e\n\u003cli\u003eFoster AC, Kemp JA. \"Glutamate- and GABA-based CNS therapeutics.\"\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eCurr Opin Pharmacol\u003c\/span\u003e. 2006 Feb;6(1):7-17. Epub 2005 Dec 22.\u003c\/li\u003e\n\u003cli\u003eChung BY, Kilman VL, Keath JR, Pitman JL, Allada R. \"The GABA(A) Receptor RDL Acts in Peptidergic PDF Neurons to Promote Sleep in Drosophila.\"\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eCurr Biol\u003c\/span\u003e. 2009 Feb 18.\u003c\/li\u003e\n\u003cli\u003eMatsuki T, Nomiyama M, Takahira H, Hirashima N, Kunita S, Takahashi S, Yagami KI, Kilduff TS, Bettler B, Yanagisawa M, Sakurai T. \"Selective loss of GABAB receptors in orexin-producing neurons results in disrupted sleep\/wakefulness architecture.\"\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eProc Natl Acad Sci U S A\u003c\/span\u003e. 2009 Feb 25.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp class=\"supfacts\"\u003e \u003c\/p\u003e\n\u003cp class=\"supfacts\"\u003e \u003c\/p\u003e\n\u003cul class=\"callout-box\"\u003e\u003c\/ul\u003e","brand":"TranscendMe","offers":[{"title":"Default Title","offer_id":7563514052669,"sku":"RNT072-9-1","price":23.93,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0012\/6065\/0557\/products\/Gaba_mockup.jpg?v=1537486412"},{"product_id":"vitamin-d3-supplement","title":"Vitamin D3, 1500IU","description":"\u003cul class=\"callout-box\"\u003e\n\u003cli\u003eOptimum form and dose\u003c\/li\u003e\n\u003cli\u003eMaintain bone health\u003c\/li\u003e\n\u003cli\u003eSupport healthy eyes\u003c\/li\u003e\n\u003cli\u003eProtect teeth\u003c\/li\u003e\n\u003cli\u003eAvoid deficiency\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eVitamin D\u003c\/strong\u003e has been studied for a number of exciting applications and is emerging as a key nutrient for long term health. It is needed to utilize calcium and phosphorus in the body, to promote bone growth, and to maintain bone density.\u003c\/p\u003e\n\u003cp\u003eThe two main forms of Vitamin D are Ergocalciferol (D2), primarily derived from diet, and Cholecalciferol (D3), synthesized within the body when the skin is exposed to UVB rays.\u003c\/p\u003e\n\u003cp\u003eVitamin D2 is found in high concentrations in mushrooms (a rare source of D for vegans) and in moderate concentrations in fatty fish, such as wild salmon. However, it's difficult to get enough vitamin D from food. In some countries, foods like cereals, milk and margarine are fortified to include moderate levels of the vitamin, but many of these foods are not ideal to consume in large amounts.\u003c\/p\u003e\n\u003cp\u003eSmog, latitude, sunscreen and time of day all impact the amount of D3 your skin can make from the sun in any given period. Although vitamin D is a fat soluble vitamin, it can only be stored in the body for sixty days, increasing the risk of deficiency in climates with shorter summers and less daylight hours.\u003c\/p\u003e\n\u003ch5\u003eIngredients\u003c\/h5\u003e\n\u003cmeta charset=\"utf-8\"\u003e\n\u003ch6\u003eOther Ingredients:\u003c\/h6\u003e\n\u003cspan\u003eDicalcium phosphate, microcrystalline cellulose, vegetable stearic acid, vegetable magnesium stearate, pharmaceutical glaze, silicon dioxide and croscarmellose sodium.\u003c\/span\u003e\n\u003ch6\u003eALLERGEN WARNING:\u003c\/h6\u003e\n\u003cspan\u003eThis product is manufactured and packaged in a facility which may also process milk, soy, wheat, egg, peanuts, tree nuts, fish and crustacean shellfish.\u003c\/span\u003e\n\u003ch6\u003eCAUTION:\u003c\/h6\u003e\n \u003cspan\u003eDo not exceed recommended dose. This product is not intended for pregnant or nursing mothers, children under the age of 18, or persons with a known medical condition. If you have questions about the advisability of taking this product, consult your physician prior to use. This product is manufactured and packaged in a facility which may also process milk, soy, wheat, egg, peanuts, tree nuts, fish and crustacean shellfish.\u003c\/span\u003e\n\u003ch6\u003eContains No:\u003c\/h6\u003e\n\u003cspan\u003e Yeast, Sugar, Starch, Artificial Colors, Flavors or Preservatives.\u003c\/span\u003e\n\u003ch6\u003eSuggested Use:\u003c\/h6\u003e\n\u003cspan\u003eAs a dietary supplement, take one (1) tablet daily.\u003c\/span\u003e\n\u003cp\u003eKurzweil \u0026amp; Grossman's D3 contains 120 tablets per bottle.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch5\u003eMore Info\u003c\/h5\u003e\n\u003cmeta charset=\"utf-8\"\u003e\n\u003cp\u003eAs we age, our need for vitamin D increases. However, the ability of the skin to make D3 and the capacity of the kidneys to utilize the compounds both decrease with age. Older people and women with low sunlight exposure and\/or milk intake are the most likely candidates for dietary deficiencies in vitamin D. Individuals in northern climates and those with dark skin (the additional melanin makes D3 synthesis by sunlight take longer) are also likely candidates.\u003c\/p\u003e\n\u003cp\u003eWith deficiency, there is a decrease in production of the protein that helps enable calcium absorption, which can lead to weakened bones. Vitamin D deficiency has also been linked to certain cancers, immune weakness and diabetes.\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eA study of 708 men and 1,058 women found an association between cognitive impairment and low levels of vitamin D in the blood. The participant group with the lowest vitamin D levels had more than twice as many instances of cognitive impairment.\u003csup\u003e8\u003c\/sup\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eThe best way to find out if you have a Vitamin D deficiency is to check your blood level with a 25(OH) test, which can be easily performed by any physician. The normal range is 32 to 100 nanograms per milliliter, but Kurzweil \u0026amp; Grossman recommend maintaining a level of at least 50 nanograms.\u003c\/p\u003e\n\u003cp\u003eAlthough there is a risk for toxicity with excessive D intake, research indicates the current RDA and UL (official minimum and maximum intakes) are too low. TRANSCEND suggests 600-2,000 IUs of Vitamin D per day for almost everyone as part of their universal supplement recommendations. If your level is under 30, we suggest 5,000 IU per day until your level improves. Each vegetarian tablet of our formula contains 1500 IUs of the D3 form of Vitamin D. If you are trying to maintain a high level, we recommend regular blood monitoring to avoid toxicity.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch5\u003eReferences\u003c\/h5\u003e\n\u003cmeta charset=\"utf-8\"\u003e\n\u003col class=\"supfact\"\u003e\n\u003cli\u003eAmerican Medical Women's Association. \"Vitamin D and Your Bone Health.\"\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"http:\/\/www.amwa-doc.org\/index.cfm?objectid=974574C7-D567-0B25-51ED183FD9BE2CF5\" target=\"_blank\" rel=\"noopener noreferrer\"\u003ehttp:\/\/www.amwa-doc.org\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eMayo Clinic Patient Monograph. \"Vitamin D.\"\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"http:\/\/www.mayoclinic.com\/health\/vitamin-d\/NS_patient-vitamind\" target=\"_blank\" rel=\"noopener noreferrer\"\u003ehttp:\/\/www.mayoclinic.com\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eArch Ophthalmol. 2007;125:661-669. Niyati Parekh et al.\u003c\/li\u003e\n\u003cli\u003eJ Periodontol 2005;76:1576-1587. Dr. Charles F. Hildebolt.\u003c\/li\u003e\n\u003cli\u003eGloth FM 3d, Gundberg CM, Hollis BW, Haddad JG Jr, Tobin JD. \"Vitamin D deficiency in homebound elderly persons.\" JAMA 1995;274:1683-6.\u003c\/li\u003e\n\u003cli\u003eLooker AC, Dawson-Hughes B, Calvo MS, Gunter EW, Sahyoun NR. Serum 25-hydroxyvitamin D status of adolescents and adults in two seasonal subpopulations from NHANES III. Bone 2002;30:771-7.\u003c\/li\u003e\n\u003cli\u003eAMWA. \"Vitamin D and Your Bone Health.\"\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"http:\/\/www.amwa-doc.org\/index.cfm?objectid=974574C7-D567-0B25-51ED183FD9BE2CF5\" target=\"_blank\" rel=\"noopener noreferrer\"\u003ehttp:\/\/www.amwa-doc.org\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eLlewellyn DJ, Langa K, Lang I. \"Serum 25-Hydroxyvitamin D Concentration and Cognitive Impairment.\" J Geriatr Psychiatry Neurol. 2008 Dec 10.\u003cspan\u003e \u003c\/span\u003e\u003ca target=\"_blank\" href=\"http:\/\/jgp.sagepub.com\/cgi\/content\/abstract\/0891988708327888v2\" rel=\"noopener noreferrer\"\u003ehttp:\/\/jgp.sagepub.com\/\u003c\/a\u003e \u003c\/li\u003e\n\u003c\/ol\u003e","brand":"TranscendMe","offers":[{"title":"Default Title","offer_id":7563518869565,"sku":"RNT217-4-1","price":13.19,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0012\/6065\/0557\/products\/Vit.D3_mockup.jpg?v=1536791208"}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0012\/6065\/0557\/collections\/gettyimages-1353382289-2048x2048.jpg?v=1663679337","url":"https:\/\/transcend.me\/collections\/mental-health-supplements-for-fall-1.oembed?constraint=bones-joints","provider":"TRANSCEND","version":"1.0","type":"link"}